Targeted Preventive Maintenance of Pharmaceutical Equipment
Issue:
Volume 4, Issue 2, June 2018
Pages:
10-15
Received:
24 April 2018
Accepted:
5 June 2018
Published:
4 July 2018
Abstract: To study effective management mode for preventive maintenance of equipment in pharmaceutical enterprises. Different pharmaceutical equipment has different importance in the producing process, so maintenance to each equipment should be different. A targeted maintenance reqiures to classify equipment and its components. To this aim, with help of assessment tools such as System Impact Assessment(SIA), Component Criticality Assessment(CCA) and deision-making grip, the specific targeted maintenance plan can be made and then implement it. Check the effect and feed back the problems. According to assess result of SIA & CCA, and deision-making grip, Pharmaceutical equipment can be classified into key equipment, important equipment and insignificant equipment. Components of equipment can be divided into two levels, critical and non-critical. For critical components of key equipment, comprehensive maintenance is needed. Maintenance of non-critical parts of key equipment and critical parts of important equipment should be paid great attention to. As for non-critical parts of important equipment and insignificant equipment, daily maintenance is enough. Such maintenance plan makes a distinction between the important equipment and the lesser ones. Through targeted management, preventive maintenance effect can be improved.
Abstract: To study effective management mode for preventive maintenance of equipment in pharmaceutical enterprises. Different pharmaceutical equipment has different importance in the producing process, so maintenance to each equipment should be different. A targeted maintenance reqiures to classify equipment and its components. To this aim, with help of asse...
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In Vitro Antimicrobial Activity and GC-MS Analysis of Seed Extracts from Pimpinella anisum L
Ayat Ahmed Alrasheid,
Babeker Siddig Abdallah,
Amar Osman Ali
Issue:
Volume 4, Issue 2, June 2018
Pages:
16-21
Received:
1 June 2018
Accepted:
1 July 2018
Published:
24 July 2018
Abstract: Pimpinella anisum L. (family Apiaceae) is widely used for curing variety of ailments. The objective of this study was to evaluate the antimicrobial activity and chemical composition of chloroform and ethanol extracts from the seed of Pimpinella anisum against standard microorganism. This plant has been used as a traditional treatment for several diseases such as microbial infections. Extracts were evaluated for their effectiveness against four bacterial strains including both Gram-positive (Bacillus subtilis and Staphylococcus aureus) and Gram-negative (Escherichia coli and Pseudomonas aeruginosa) bacteria as well as fungal species (Candida albicans and Aspergillus niger) using disc diffusion method. The chloroform extract showed the highest activity against B.subtilis (11 mm), E. coli (16mm) and P. aeruginosa (14.5 mm) but the same result against S. aureus in two extracts (15.5 mm). All extracts exhibited high antifungal activity against C. albicans and A. niger with inhibition zone ranging from (14.5 to 20 mm). The quantitative analysis of chemical composition determined by Gas Chromatography–Mass Spectrometry (GC-MS). The result showed high amounts of Butanoic acid, 2-methyl-, 2-methoxy-4-(2-propenyl) phenyl ester (23.21%) and Anethole (12.52%).
Abstract: Pimpinella anisum L. (family Apiaceae) is widely used for curing variety of ailments. The objective of this study was to evaluate the antimicrobial activity and chemical composition of chloroform and ethanol extracts from the seed of Pimpinella anisum against standard microorganism. This plant has been used as a traditional treatment for several di...
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