Current Issue: Vol. 4, Issue 3, September 2018
Frequency:  Quarterly
ISSN Print:  2472-355X
ISSN Online:  2472-3576
Latest Articles
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Rajaganapathy Kaliyaperumal, Manjunatha Panduranga Mudugal, Prashantha Nagaraja, Nageena Taj
Pages: 22-34   Published Online: Nov. 5, 2018
DOI: 10.11648/j.jddmc.20180403.11
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Ayat Ahmed Alrasheid, Babeker Siddig Abdallah, Amar Osman Ali
Pages: 16-21   Published Online: Jul. 24, 2018
DOI: 10.11648/j.jddmc.20180402.12
View  634          Downloads  67
Hao Yinghua, Liang Yi
Pages: 10-15   Published Online: Jul. 4, 2018
DOI: 10.11648/j.jddmc.20180402.11
View  696          Downloads  61
Hongcai Zhang, Baosheng Liu, Xu Cheng, Jinju Wang
Pages: 5-9   Published Online: Jun. 28, 2018
DOI: 10.11648/j.jddmc.20180401.12
View  668          Downloads  36
Xiao Ruisen, Huang Ping, Wang Hong, Li Jinwei
Pages: 1-4   Published Online: Jun. 19, 2018
DOI: 10.11648/j.jddmc.20180401.11
View  813          Downloads  42
Hermann N'Guessan, Eugene Megnassan
Pages: 86-113   Published Online: Jan. 11, 2018
DOI: 10.11648/j.jddmc.20170306.13
View  1755          Downloads  115
Sandeep Patnaik, Aditya Dileep Kurdekar, Lakshmi Adinarayana Avinash Chunduri, Chinnakoti Prathibha, Kamisetti Venkataramaniah
Pages: 77-85   Published Online: Nov. 23, 2017
DOI: 10.11648/j.jddmc.20170306.11
View  1862          Downloads  113
Ijeoma Solomon Okoro, Sampson Dominic Umoh, John Vershima Anyam, Manasseh Msugh-Ter Manyi, Cynthia Adegbe
Pages: 71-76   Published Online: Nov. 20, 2017
DOI: 10.11648/j.jddmc.20170305.12
View  1784          Downloads  84
Research Topics
Research Topic is an innovative academic concept focusing on the hottest areas in academia, here gathered a variety of current research active areas and issues. You can browse the topics you are interested in and offer new topics for others.
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Research Topic #1
Drug discovery
In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered through identifying the active ingredient from traditional remedies or by serendipitous discovery. Modern drug discovery involves the identification of screening hits, medicinal chemistry and optimization of those hits to increase the affinity, selectivity (to reduce the potential of side effects), efficacy/potency, metabolic stability (to increase the half-life), and oral bioavailability.
Research Topic #2
Drug design
Drug design, often referred to as rational drug design or simply rational design, is the inventive process of finding new medications based on the knowledge of a biological target. The drug is most commonly an organic small molecule that activates or inhibits the function of a biomolecule such as a protein, which in turn results in a therapeutic benefit to the patient. In the most basic sense, drug design involves the design of molecules that are complementary in shape and charge to the biomolecular target with which they interact and therefore will bind to it.
Research Topic #3
Computational chemistry
Computational chemistry is a branch of chemistry that uses computer simulation to assist in solving chemical problems. It uses methods of theoretical chemistry, incorporated into efficient computer programs, to calculate the structures and properties of molecules and solids. It is necessary because, apart from relatively recent results concerning the hydrogen molecular ion, the quantum many-body problem cannot be solved analytically, much less in closed form. While computational results normally complement the information obtained by chemical experiments, it can in some cases predict hitherto unobserved chemical phenomena. It is widely used in the design of new drugs and materials.
Research Topic #4
Synthetic organic chemistry
Synthetic organic chemistry is an applied science as it borders engineering, the "design, analysis, and/or construction of works for practical purposes". Organic synthesis of a novel compound is a problem solving task, where a synthesis is designed for a target molecule by selecting optimal reactions from optimal starting materials. Complex compounds can have tens of reaction steps that sequentially build the desired molecule. The synthesis proceeds by utilizing the reactivity of the functional groups in the molecule.
Special Issues
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Editorial Board
Lina Ding
Department of Pharmacy, Zhengzhou University, Zhengzhou, Henan, China
Sarbjit Singh
Department of Chemistry, University of Texas at Dallas, Dallas, Texas, USA
Xiaoyun Lu
College of Pharmacy, Jinan University, Guangzhou, Guangdong, China
Yulong Xu
Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA
Rakeshchandra Meka
Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, USA
Peer Reviewer
Xufen Yu
Department of Pharmacological Science, Icahn School of Medicine at Mount Sinai, New York, USA
Silvia Stotani
Department of Drug Sciences, Medicinal Chemistry and Pharmaceutical Technology Section, University of Pavia, Pavia, Italy
Marwa El-Wakil
Department of Pharmaceutical Chemistry, Alexandria University, Alexandria, Egypt
Xin Li
Department of Pharmacological and Pharmaceutical Sciences, University of Houston, Houston, Texas, USA
Zhibo Jiang
NHC Key Laboratory of Biotechnology of Antibiotics, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
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