Journal of Drug Design and Medicinal Chemistry

Volume 3, Issue 3, June 2017

  • Hepatoprotective Effect of Aqueous Extract of Telfairia occidentalis on Cadmium Chloride-Induced Oxidative Stress and Hepatotoxicity in Rats

    Johnson Olaleye Oladele, Olu Israel Oyewole, Olamilekan Kabiru Bello, Oluwaseun Titilope Oladele

    Issue: Volume 3, Issue 3, June 2017
    Pages: 32-36
    Received: Apr. 06, 2017
    Accepted: Apr. 21, 2017
    Published: Jul. 04, 2017
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    Abstract: Cadmium and its compounds have been classified as known human carcinogens. Telfairia occidentalis is a medicinal plant with a number of pharmacological activities attributed to its extracts. This study was designed to investigate the possible hepatoprotective effect of aqueous extract of Telfairia occidentalis on cadmium chloride (CdCl2) induced ox... Show More
  • Use of Solid Dispersions and Inclusion Complexation for Enhancing Oral Bioavailability of Ziprasidone in Treating Schizophrenia

    Poonam Mogal, Deeliprao Derle

    Issue: Volume 3, Issue 3, June 2017
    Pages: 37-48
    Received: May 19, 2017
    Accepted: Jun. 21, 2017
    Published: Jul. 25, 2017
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    Abstract: In modern times, people are suffering from many mental health disorders like schizophrenia, bipolar disorders and many psychoses. Hence, it is essential to treat these mental disorders using medications as well as with assistance from caregivers for the social well being of person. This study was focussed on improving solubility & dissolution of po... Show More