Journal of Drug Design and Medicinal Chemistry

Volume 4, Issue 1, March 2018

  • Study on the Extraction Rate of Morphine Before and After Hair Grinding

    Xiao Ruisen, Huang Ping, Wang Hong, Li Jinwei

    Issue: Volume 4, Issue 1, March 2018
    Pages: 1-4
    Received: May 03, 2018
    Accepted: May 30, 2018
    Published: Jun. 19, 2018
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    Abstract: 1500 morphine-absorbed hair was collected, and the hair was ground with a quick grinder to extract the morphine component of the hair. The morphine was qualitatively detected by gas chromatography/mass spectrometry (GC/MS). The test results were processed by statistical software and the hair was evaluated. Morphine positive tests results. A total o... Show More
  • Comparative Studies on the Interaction Between the Medicine Small Molecule with Pepsin by Fluorescence Quenching Spectroscopy and Improved Spectroscopy

    Hongcai Zhang, Baosheng Liu, Xu Cheng, Jinju Wang

    Issue: Volume 4, Issue 1, March 2018
    Pages: 5-9
    Received: May 04, 2018
    Accepted: Jun. 07, 2018
    Published: Jun. 28, 2018
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    Abstract: The binding mechanism between cefetamet pivoxil (CFP) and pepsin (PEP) at different temperatures (298 K, 303 K, 310 K) was investigated by the classical fluorescence spectroscopy with focus on the fluorescence change of protein, as well as the improved spectroscopy with focus on the fluorescence changes of the resonance light scattering of small mo... Show More